The methods used are accredited by UKAS to ISO / IEC 17025:2015. Endotoxins are released as a result of the breakdown of Gram Negative bacteria. Endotoxins are also known as pyrogens because they cause fever and inflammation in humans. A sterile device or water sample could still contain high levels of endotoxin which could cause illness in a patient. The laboratory uses Limulus Amoebocyte Lysate (LAL) tests to detect amounts of endotoxin. [Testing Water for Endotoxin (pyrogens)](/pages/water_endotoxin.php). [Testing Medical Devices for Endotoxin (pyrogens)](/pages/medical_endotoxin.php).